abstract：BACKGROUND:Researchers are required to seek consent from Indigenous communities prior to conducting research but there is inadequate information about how Indigenous people understand and become fully engaged with this consent process. Few studies evaluate the preference or understanding of the consent process for rese...

journal_title：BMC medical ethics

authors： Fitzpatrick EFM,Macdonald G,Martiniuk ALC,D'Antoine H,Oscar J,Carter M,Lawford T,Elliott EJ

更新日期：2017-05-11 00:00:00

abstract：BACKGROUND:Despite the growing recognition for the need to improve the health of prisoners in Canada and the need for health research, there has been little discussion of the ethical issues with regards to health research with prisoners in Canada. The purpose of this paper is to encourage a national conversation about ...

journal_title：BMC medical ethics

authors： Silva DS,Matheson FI,Lavery JV

更新日期：2017-04-27 00:00:00

abstract：BACKGROUND:Professional guidelines have addressed ethical dilemmas posed by a few types of nontraditional procreative arrangements (e.g., gamete donations between family members), but many questions arise regarding how providers view and make decisions about these and other such arrangements. METHODS:Thirty-seven ART ...

journal_title：BMC medical ethics

authors： Klitzman R

更新日期：2017-02-28 00:00:00

abstract：BACKGROUND:The past 10 years have witnessed a significant growth in sharing of health data for secondary uses. Alongside this there has been growing interest in the public acceptability of data sharing and data linkage practices. Public acceptance is recognised as crucial for ensuring the legitimacy of current practice...

journal_title：BMC medical ethics

authors： Aitken M,de St Jorre J,Pagliari C,Jepson R,Cunningham-Burley S

更新日期：2016-11-10 00:00:00

abstract：BACKGROUND:A child is a developing person with evolving capacities that include autonomy, mental (decisional) capacity and capacity to assume responsibility. Hence, children are entitled to participatory (autonomy) rights in South Africa as observed in the Children's Act 38 of 2005. According to section 129 of the Act ...

journal_title：BMC medical ethics

authors： Ganya W,Kling S,Moodley K

更新日期：2016-11-02 00:00:00

abstract：BACKGROUND:When conducting research with Indigenous populations consent should be sought from both individual participants and the local community. We aimed to search and summarise the literature about methods for seeking consent for research with Indigenous populations. METHODS:A systematic literature search was cond...

journal_title：BMC medical ethics

authors： Fitzpatrick EF,Martiniuk AL,D'Antoine H,Oscar J,Carter M,Elliott EJ

更新日期：2016-10-22 00:00:00

abstract：BACKGROUND:When a new intervention or drug is developed, this has to pass through various phases of clinical testing before it achieves market approval, which can take many years. This raises an issue for drugs which could benefit terminally ill patients. These patients might set their hopes on the experimental drug bu...

journal_title：BMC medical ethics

authors： Raus K

更新日期：2016-10-18 00:00:00

abstract：:Pediatric biobanking is considered important for generating biomedical knowledge and improving (pediatric) health care. However, the inclusion of children's samples in biobanks involves specific ethical issues. One of the main concerns is how to appropriately engage children in the consent procedure. We suggest that c...

journal_title：BMC medical ethics

authors： Giesbertz NA,Melham K,Kaye J,van Delden JJ,Bredenoord AL

更新日期：2016-10-12 00:00:00

abstract：BACKGROUND:Respect for confidentiality is important to safeguard the well-being of patients and ensure the confidence of society in the doctor-patient relationship. The aim of our study is to examine real situations in which there has been a breach of confidentiality, by means of direct observation in clinical practice...

journal_title：BMC medical ethics

authors： Beltran-Aroca CM,Girela-Lopez E,Collazo-Chao E,Montero-Pérez-Barquero M,Muñoz-Villanueva MC

更新日期：2016-09-02 00:00:00

abstract：BACKGROUND:In most Anglophone nations, policy and law increasingly foster an autonomy-based model, raising issues for large numbers of people who fail to fit the paradigm, and indicating problems in translating practical and theoretical understandings of 'good death' to policy. Three exemplar populations are frail olde...

journal_title：BMC medical ethics

authors： Birchley G,Jones K,Huxtable R,Dixon J,Kitzinger J,Clare L

更新日期：2016-07-27 00:00:00

abstract：BACKGROUND:Over the past 25 years, there has been growing recognition of the importance of studying the Ethical, Legal and Social Implications (ELSI) of genetic and genomic research. A large investment into ELSI research from the National Institutes of Health (NIH) Human Genomic Project budget in 1990 stimulated the gr...

journal_title：BMC medical ethics

authors： Bell J,Ancillotti M,Coathup V,Coy S,Rigter T,Tatum T,Grewal J,Akcesme FB,Brkić J,Causevic-Ramosevac A,Milovanovic G,Nobile M,Pavlidis C,Finlay T,Kaye J,ELSI2.0.

更新日期：2016-07-08 00:00:00

abstract：BACKGROUND:The widespread sharing of biologicaConcluding Comments: Teaching Responsible Datal and biomedical data is recognised as a key element in facilitating translation of scientific discoveries into novel clinical applications and services. At the same time, twenty-first century states are increasingly concerned t...

journal_title：BMC medical ethics

authors： Bezuidenhout LM,Morrison M

更新日期：2016-05-17 00:00:00

abstract：BACKGROUND:Implementation science research, especially when using participatory and co-design approaches, raises unique challenges for research ethics committees. Such challenges may be poorly addressed by approval and governance mechanisms that were developed for more traditional research approaches such as randomised...

journal_title：BMC medical ethics

authors： Goodyear-Smith F,Jackson C,Greenhalgh T

更新日期：2015-11-16 00:00:00

abstract：BACKGROUND:Institutional review boards (IRBs) distinguish health care quality improvement (QI) and health care quality improvement research (QIR) based primarily on the rigor of the methods used and the purported generalizability of the knowledge gained. Neither of these criteria holds up upon scrutiny. Rather, this ap...

journal_title：BMC medical ethics

authors： Fiscella K,Tobin JN,Carroll JK,He H,Ogedegbe G

更新日期：2015-09-17 00:00:00

abstract：BACKGROUND:Appropriate information and consent has been one of the most intensely discussed topics within the context of biobank research. In parallel to the normative debate, many socio-empirical studies have been conducted to gather experiences, preferences and views of patients, healthy research participants and fur...

journal_title：BMC medical ethics

authors： D'Abramo F,Schildmann J,Vollmann J

更新日期：2015-09-09 00:00:00

abstract：BACKGROUND:Expectations of receiving personal health information as a fringe benefit of biospecimen donation-termed diagnostic misconception-are increasingly documented. We developed an instrument measuring conflation of observational biospecimen-based research and clinical care for use with Latino communities, who may...

journal_title：BMC medical ethics

authors： Knerr S,Ceballos RM

更新日期：2015-07-17 00:00:00

abstract：BACKGROUND:The boundaries between health-related research and practice have become blurred as initiatives traditionally considered to be practice (e.g., quality improvement, program evaluation) increasingly use the same methodology as research. Further, the application of different ethical requirements based on this di...

journal_title：BMC medical ethics

authors： Ondrusek NK,Willison DJ,Haroun V,Bell JA,Bornbaum CC

更新日期：2015-07-07 00:00:00

abstract：BACKGROUND:Community consultation is increasingly recommended, and in some cases, required by ethical review boards for research that involves higher levels of ethical risk such as international research and research with vulnerable populations. In designing a randomised control trial of a mental health intervention us...

journal_title：BMC medical ethics

authors： Shanks L,Moroni C,Rivera IC,Price D,Clementine SB,Pintaldi G

更新日期：2015-06-02 00:00:00

abstract：BACKGROUND:Several charters of rights have been issued in Europe to solemnly proclaim the rights of children during their hospital stay. However, notwithstanding such general declarations, the actual implementation of hospitalized children's rights is unclear. The purpose of this study was to understand to which extent...

journal_title：BMC medical ethics

authors： Bisogni S,Aringhieri C,McGreevy K,Olivini N,Lopez JR,Ciofi D,Merlo AM,Mariotti P,Festini F

更新日期：2015-05-13 00:00:00

abstract：BACKGROUND:The generation of evidence is integral to the work of public health and health service providers. Traditionally, ethics has been addressed differently in research projects, compared with other forms of evidence generation, such as quality improvement, program evaluation, and surveillance, with review of non-...

journal_title：BMC medical ethics

authors： Willison DJ,Ondrusek N,Dawson A,Emerson C,Ferris LE,Saginur R,Sampson H,Upshur R

更新日期：2014-08-08 00:00:00

abstract：BACKGROUND:Patient outcome after serious brain injury is highly variable. Following a period of coma, some patients recover while others progress into a vegetative state (unresponsive wakefulness syndrome) or minimally conscious state. In both cases, assessment is difficult and misdiagnosis may be as high as 43%. Recen...

journal_title：BMC medical ethics

authors： Weijer C,Peterson A,Webster F,Graham M,Cruse D,Fernández-Espejo D,Gofton T,Gonzalez-Lara LE,Lazosky A,Naci L,Norton L,Speechley K,Young B,Owen AM

更新日期：2014-05-20 00:00:00

abstract：BACKGROUND:Studies on informed consent to medical research conducted in low or middle-income settings have increased, including empirical investigations of consent to genetic research. We investigated voluntary participation and comprehension of informed consent among women involved in a genetic epidemiological study o...

journal_title：BMC medical ethics

authors： Marshall PA,Adebamowo CA,Adeyemo AA,Ogundiran TO,Strenski T,Zhou J,Rotimi CN

更新日期：2014-05-13 00:00:00

abstract：BACKGROUND:Donepezil, an acetylcholinesterase inhibitor used in the treatment of Alzheimer's disease, has been widely cited in media and bioethics literature on cognitive enhancement (CE) as having the potential to improve the cognitive ability of healthy individuals. In both literatures, this claim has been repeatedly...

journal_title：BMC medical ethics

authors： Wade L,Forlini C,Racine E

更新日期：2014-05-12 00:00:00

abstract：BACKGROUND:The study examined the knowledge and attitudes to personal genomics testing for complex diseases among Nigerians and identified how the knowledge and attitudes vary with gender, age, religion, education and related factors. METHODS:Data were collected using qualitative method in 2 districts of the Federal C...

journal_title：BMC medical ethics

authors： Fagbemiro L,Adebamowo C

更新日期：2014-04-27 00:00:00

abstract：BACKGROUND:The increased use of human biological material for cell-based research and clinical interventions poses risks to the privacy of patients and donors, including the possibility of re-identification of individuals from anonymized cell lines and associated genetic data. These risks will increase as technologies ...

journal_title：BMC medical ethics

authors： Ogbogu U,Burningham S,Ollenberger A,Calder K,Du L,El Emam K,Hyde-Lay R,Isasi R,Joly Y,Kerr I,Malin B,McDonald M,Penney S,Piat G,Roy DC,Sugarman J,Vercauteren S,Verhenneman G,West L,Caulfield T

更新日期：2014-02-03 00:00:00

abstract：BACKGROUND:Although informed consent is an integral part of clinical practice, its current doctrine remains mostly a matter of law and mainstream ethics rather than empirical research. There are scarce empirical data on patients' perceived purpose of informed consent, which may include administrative routine/courtesy g...

journal_title：BMC medical ethics

authors： Hammami MM,Al-Gaai EA,Al-Jawarneh Y,Amer H,Hammami MB,Eissa A,Qadire MA

更新日期：2014-01-10 00:00:00

abstract：BACKGROUND:In studies publishing identifying personal information, obtaining consent is regarded as necessary, as it is impossible to ensure complete anonymity. However, current journal practices around specific points to consider when obtaining consent, the contents of consent forms and how consent forms are managed h...

journal_title：BMC medical ethics

authors： Yoshida A,Dowa Y,Murakami H,Kosugi S

更新日期：2013-11-25 00:00:00

abstract：BACKGROUND:Efforts to improve patients' understanding of their own medical treatments or research in which they are involved are progressing, especially with regard to informed consent procedures. We aimed to design a multisource informed consent procedure that is easily adaptable to both clinical and research applicat...

journal_title：BMC medical ethics

authors： Cervo S,Rovina J,Talamini R,Perin T,Canzonieri V,De Paoli P,Steffan A

更新日期：2013-07-30 00:00:00

abstract：BACKGROUND:South Africa currently has a pluralistic health care system with separate public and private sectors. It is, however, moving towards a socialised model with the introduction of National Health Insurance. The South African legislative environment has changed recently with the promulgation of the Consumer Prot...

journal_title：BMC medical ethics

authors： Rowe K,Moodley K

更新日期：2013-03-21 00:00:00

abstract：BACKGROUND:In 2009, Dr. Paolo Zamboni proposed chronic cerebrospinal venous insufficiency (CCSVI) as a possible cause of multiple sclerosis (MS). Although his theory and the associated treatment ("liberation therapy") received little more than passing interest in the international scientific and medical communities, hi...

journal_title：BMC medical ethics

authors： Pullman D,Zarzeczny A,Picard A

更新日期：2013-02-12 00:00:00

abstract：:The 3rd Pan-African Ethics Human Rights and Medical Law (3rd EHRML) conference was held in Johannesburg on July 7, 2013, as part of the Africa Health Congress. The conference brought together bioethicists, researchers and scholars from South Africa, Zimbabwe, Kenya and Nigeria working in the field of bioethics as well...

journal_title：BMC medical ethics

authors： Chima SC,Mduluza T,Kipkemboi J

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Financial relationships between physicians and industry are extensive and public reporting of industry payments to physicians is now occurring. Our objectives were to describe physician recipients of large total payments from these seven companies, and to examine discrepancies between these payments and conf...

journal_title：BMC medical ethics

authors： Norris SL,Holmer HK,Ogden LA,Burda BU,Fu R

更新日期：2012-09-26 00:00:00

abstract：BACKGROUND:Cancer patients are at risk of developing blood clots in their veins - venous thromboembolism (VTE) - which often takes the form of a pulmonary embolism or deep vein thrombosis. The risk increases with advanced disease. Evidence based treatment is low molecular weight heparin (LMWH) by daily subcutaneous inj...

journal_title：BMC medical ethics

authors： Sheard L,Prout H,Dowding D,Noble S,Watt I,Maraveyas A,Johnson M

更新日期：2012-09-04 00:00:00

abstract：BACKGROUND:Family members are often required to act as substitute decision-makers when health care or research participation decisions must be made for an incapacitated relative. Yet most families are unable to accurately predict older adult preferences regarding future health care and willingness to engage in research...

journal_title：BMC medical ethics

authors： Bravo G,Arcand M,Blanchette D,Boire-Lavigne AM,Dubois MF,Guay M,Hottin P,Lane J,Lauzon J,Bellemare S

更新日期：2012-01-05 00:00:00

abstract：BACKGROUND:As genetics technology proceeds, practices of genetic testing have become more heterogeneous: many different types of tests are finding their way to the public in different settings and for a variety of purposes. This diversification is relevant to the discourse on ethical, legal and societal issues (ELSI) s...

journal_title：BMC medical ethics

authors： Bunnik EM,Schermer MH,Janssens AC

更新日期：2011-06-14 00:00:00

abstract：BACKGROUND:A requisite for ethical human subjects research is that participation should be informed and voluntary. Participation during the informed consent process by way of asking questions is an indicator of the extent to which consent is informed. AIMS:The aims of this study were to assess the extent to which pare...

journal_title：BMC medical ethics

authors： Rajaraman D,Jesuraj N,Geiter L,Bennett S,Grewal HM,Vaz M,TB Trials Study Group.

更新日期：2011-02-15 00:00:00

abstract：BACKGROUND:Consenting for retrospective medical records-based research (MR) and leftover tissue-based research (TR) continues to be controversial. Our objective was to survey Saudis attending outpatient clinics at a tertiary care hospital on their personal preference and perceptions of norm and current practice in rela...

journal_title：BMC medical ethics

authors： Al-Qadire MM,Hammami MM,Abdulhameed HM,Al Gaai EA

更新日期：2010-10-18 00:00:00

abstract：BACKGROUND:There is a permanent need to evaluate and develop the ethical quality of scientific research and to widen knowledge about the effects of ethical issues. Therefore we evaluated whether informed consent is related to implementation and success in a lifestyle intervention study with older research participants....

journal_title：BMC medical ethics

authors： Länsimies-Antikainen H,Pietilä AM,Laitinen T,Kiviniemi V,Rauramaa R

更新日期：2010-06-08 00:00:00

abstract：BACKGROUND:Africa continues to bear a disproportionate share of the global HIV/AIDS, tuberculosis (TB) and malaria burden. The development and distribution of safe, effective and affordable vaccines is critical to reduce these epidemics. However, conducting HIV/AIDS, TB, and/or malaria vaccine trials simultaneously in ...

journal_title：BMC medical ethics

authors： Mamotte N,Wassenaar D,Koen J,Essack Z

更新日期：2010-03-09 00:00:00

abstract：BACKGROUND:Intensive care physicians often must rely on substitute decision makers to address all dimensions of the construct of "best interest" for incapable, critically ill patients. This task involves identifying prior wishes and to facilitate the substitute decision maker's understanding of the incapable patient's ...

journal_title：BMC medical ethics

authors： Ratnapalan M,Cooper AB,Scales DC,Pinto R

更新日期：2010-02-10 00:00:00